AbbVie Showcases New Analyses and Real-World Data Across Multiple Immune-Mediated Skin Diseases at the European Academy of Dermatology and Venereology (EADV) 2022 Congress

  • Analyses highlight long-term efficacy and safety results, including real-world data, from studies of SKYRIZI® (risankizumab) in moderate to severe psoriasis and active psoriatic arthritis
  • Presentations include data from the largest-of-its-kind study that demonstrates the real-world burden of atopic dermatitis
  • Breadth of data underscores AbbVie’s commitment to advancing research in dermatology for people living with immune-mediated skin diseases such as psoriasis, psoriatic arthritis, atopic dermatitis and vitiligo

AbbVie( NYSE ABBV) moment blazoned it’ll present 23 objectifications at the 31st European Academy of Dermatology and Venereology( EADV) Congress, including a late- breaking oral donation on long- term efficacity and safety data of SKYRIZI ®( risankizumab) in psoriatic arthritis and real- world data from MEASURE- announcement to assess the multidimensional burden of atopic dermatitis. This exploration demonstrates AbbVie’s commitment to heightening the understanding of vulnerable- mediated skin conditions by investing in studies of delicate- to- treat case populations, certain complaint areas with many living treatment options as well as real- world patient experience. The mongrel congress will take place from September 7- 10, in Milan, as well as nearly.

” Our leadership in dermatology runs deep – from developing innovative technologies to studying lower- understood conditions where many to no treatment options presently live,” said Chiedzo Mpofu, MBChB,Ph.D., vice chairman, Global Medical Affairs, Immunology, AbbVie.” At this time’s EADV Congress, we are presenting a range of data, including real- world, case- centered exploration that will help elevate the community’s understanding of the long- term impact of our treatments and the eventuality to support cases with delicate- to- treat conditions.”
Crucial data to be presented include

Late- breaking oral donation of new data from the ongoing Phase 3 active psoriatic arthritis clinical trials, memorial 1 and memorial 2, assessing long- term efficacity and safety, up to 100 weeks, in cases treated with SKYRIZI( risankizumab)
Analyses from MEASURE- AD, across-sectional, 28- country, burden of complaint study aimed to characterize global treatment patterns, healthcare resource application and costs, and the clinical and profitable burden of moderate to severe atopic dermatitis


Results from VALUE, a 13- month interim analysis from a long- term, prospective experimental study that has enrolled,700 cases from 21 countries, assessing real- world efficacity, continuity of response and time to first treatment change for moderate to severe psoriasis cases treated with SKYRIZI( risankizumab) compared to other generally used treatments


Results from aIMM, a Phase 3b, multicenter, interventional, open- marker, single- arm study assaying clinical efficacity, safety and quality- of- life issues after 16 weeks of treatment with SKYRIZI( risankizumab) in psoriasis cases who preliminarily achieved sour responses to one of two IL- 17 impediments, either secukinumab or ixekizumab


Interim analysis of the nearly 5- time( 256 weeks) LIMMitless open- marker extension study assessing long- term efficacity and safety data with nonstop SKYRIZI( risankizumab) treatment in cases with moderate to severe shrine psoriasis
Two real- world insurance claims database analyses examining profitable and comorbidity impacts on cases with vitiligo

SKYRIZI is part of a collaboration between Boehringer Ingelheim and AbbVie, with AbbVie leading the development and commercialization of SKYRIZI encyclopedically.

About SKYRIZI ®( risankizumab)
SKYRIZI is an interleukin- 23( IL- 23) asset that widely blocks IL- 23 by binding to its p19 subunit. IL- 23, a cytokine involved in seditious processes, is allowed
to be linked to a number of habitual vulnerable- mediated conditions,2 Phase 3 trials of SKYRIZI in psoriasis, psoriatic arthritis, Crohn’s complaint and ulcerative colitis areongoing.3- 5

US suggestions and Important Safety Information about SKYRIZI ®( risankizumab- rzaa) 2
SKYRIZI is a tradition drug used to treat grown-ups with

moderate to severe shrine psoriasis who may profit from taking injections or capsules( systemic remedy) or treatment using ultraviolet or UV light( phototherapy).
active psoriatic arthritis( PsA).
moderate to severe Crohn’s complaint.

About RINVOQ ®( upadacitinib)
Discovered and developed by AbbVie scientists, RINVOQ is a picky JAK asset that’s being studied in several vulnerable- mediated seditious conditions.6 Grounded on enzymatic and cellular assays, RINVOQ demonstrated lesser inhibitory energy for JAK- 1 vs JAK- 2, JAK- 3 and TYK-2.6 The applicability of inhibition of specific JAK enzymes to remedial effectiveness and safety isn’t presently known. Phase 3 trials of RINVOQ in atopic dermatitis, axial spondylarthritis, Crohn’s complaint, giant cell arteritis, psoriatic arthritis, rheumatoid arthritis, Takayasu arteritis and ulcerative colitis are,7- 15


About AbbVie in Dermatology
For further than a decade, AbbVie has worked to uncover new results and ameliorate care for people with serious skin conditions, including psoriasis, psoriatic arthritis, hidradenitis suppurativa and atopic dermatitis. With a broad clinical trial program, we continue to laboriously probe and acclimatize to the evolving requirements of the dermatology community and advance our channel to help people achieve their treatment pretensions and live beyond their skin complaint. For further information on AbbVie in dermatology, visit https//www.abbvie.com/our-science/therapeutic-focus-areas/immunology/immunology-focus-areas/dermatology.html.

About AbbVie
AbbVie’s charge is to discover and deliver innovative drugs that break serious health issues moment and address the medical challenges of hereafter. We strive to have a remarkable impact on people’s lives across several crucial remedial areas immunology, oncology, neuroscience, eye care, virology, women’s health and gastroenterology, in addition to products and services across our Allergan Aesthetics portfolio.

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