Angelalign Technology Reports 2025 Results, Highlighting Clinical Excellence as a Key Driver of Global Expansion
Angelalign Technology Inc. (6699.HK) has announced its financial results for the fiscal year 2025, reporting strong performance across both its domestic China market and international operations. The Company delivered significant growth in case volume, revenue, and adjusted profitability, reflecting continued expansion of its global orthodontic business and increasing adoption of clear aligner solutions among dental professionals worldwide.
For the fiscal year ended 2025, Angelalign reported total case volume of 532,400 cases, representing a year-over-year increase of 48.1%. Revenue reached approximately USD 370.3 million, marking a 37.8% increase compared to the prior year. Adjusted net profit rose to USD 43.8 million, an increase of 63.0% year-over-year. The Company attributed these results to its continued focus on clinical excellence, product innovation, and the strength of its open and inclusive organizational culture, which fosters collaboration across teams and geographies.
Angelalign’s management emphasized that its growth strategy is deeply rooted in its ability to bring together talented professionals from diverse backgrounds who share a common commitment to delivering high-quality orthodontic solutions. The Company highlighted that its culture plays a central role in enabling cross-functional collaboration between clinicians, engineers, researchers, and operational teams, allowing it to respond effectively to the evolving needs of customers in different markets.
Fox Hu, Chief Executive Officer of Angelalign Technology, commented on the results, noting that the clear aligner industry is inherently complex and multidisciplinary. According to Hu, success in this field requires not only advanced technical capabilities but also seamless coordination among professionals across regions. He explained that Angelalign’s open and inclusive environment attracts individuals who are dedicated to clinical excellence and committed to delivering superior products and services. This collaborative ecosystem, he added, continues to drive the Company’s long-term growth and competitive positioning.
A key driver of Angelalign’s global expansion has been the growing influence of premium orthodontists in major metropolitan markets. The Company explained that clear aligner treatments often involve long treatment cycles, sometimes consisting of dozens or even hundreds of aligners per case. Over the course of treatment, even subtle differences in product quality, treatment planning, and clinical execution can accumulate and significantly impact outcomes.
Premium orthodontists, who typically develop their expertise over many years, tend to rely heavily on peer feedback and shared clinical experiences within professional communities. Their collective evaluations and recommendations often shape broader adoption trends within the industry. Recognizing this dynamic, Angelalign adopted a strategy focused on directly engaging with leading orthodontists in major global cities, providing them with localized clinical support, training, and service infrastructure.
This approach required substantial investments over several years, as the Company worked to establish a presence in key international markets and build trust among high-level practitioners. According to the Company, these efforts have now begun to yield results. Angelalign has developed a strong reputation among premium orthodontists in leading cities worldwide, particularly among those who prioritize clinical precision and treatment predictability.
The Company reported that hundreds of orthodontists have each completed more than 100 cases using Angelalign’s solutions, with some clinicians having completed over 1,000 cases, including complex orthodontic treatments. Positive word-of-mouth recommendations from these experienced practitioners are contributing to broader adoption across the orthodontic community. As clinicians gain deeper insights into treatment outcomes and the performance of different aligner systems, Angelalign believes its products are increasingly recognized for their clinical reliability and consistency.
In addition to its core aligner offerings, Angelalign continues to expand its portfolio of proprietary innovations designed to address specific clinical challenges. One notable example is the angelButton™ solution, introduced approximately six years ago. Since its launch, the Company has shipped more than 100 million angelButtons globally. This accessory is designed to enhance anchorage and improve treatment efficiency through the use of specialized movement protocols.
Feedback from clinicians has played a central role in refining the performance and stability of the angelButton™ system. Over time, iterative improvements based on real-world clinical usage have contributed to enhanced predictability and reliability. Another example is the A6 Mandibular Advancement solution, which has benefited from more than a decade of clinical feedback and is designed to address mandibular development issues, particularly in younger patients. This solution reflects the Company’s broader innovation philosophy, which emphasizes solving practical clinical challenges rather than focusing solely on emerging technological trends.
Angelalign stated that its innovation strategy is grounded in long-term clinical validation and continuous improvement. Rather than prioritizing short-term technological novelty, the Company focuses on developing solutions that deliver consistent, reproducible outcomes in real-world settings. This approach requires close collaboration with leading orthodontists, whose insights help guide product development and ensure that new solutions align with clinical needs.
The Company’s open and inclusive culture supports this collaborative model by enabling feedback to flow freely between internal teams and external partners. Angelalign organizes its research and development, clinical support, sales, and operations functions in a flexible structure that allows it to respond effectively to local market conditions. This structure supports the Company’s operations in more than 60 countries worldwide.
To support its global footprint, Angelalign has established dedicated teams across five major regions: Europe, the Middle East and Africa (EMEA), North America, Asia-Pacific (APAC), South America, and China. Each region is supported by specialized education and training programs, clinical support teams, and experienced sales personnel. The Company has also developed treatment design centers in China, Brazil, and Southeast Asia, along with manufacturing facilities located in China, the United States, and Brazil.
Alongside its operational expansion, Angelalign continues to strengthen its compliance systems, data security protocols, and intellectual property portfolio. These efforts are aimed at safeguarding its innovations while ensuring adherence to regulatory requirements across different jurisdictions.
International markets played a significant role in the Company’s 2025 performance. Excluding mainland China, Angelalign recorded 256,200 cases globally, representing an 82.1% increase year-over-year. Revenue from these markets reached USD 163.0 million, an increase of 102.5% compared to the previous year. Growth in international markets has been driven largely by the adoption of Angelalign’s solutions among premium orthodontists and the increasing visibility of its clinical outcomes, particularly in complex cases.
In its domestic China market, Angelalign operates within a multi-tiered environment characterized by regional differences in practitioner expertise, patient demographics, and service delivery models. In first- and second-tier cities, the Company continues to provide advanced clinical support to orthodontists, enabling them to achieve high-quality outcomes. During 2025, Angelalign introduced new solutions designed to address more complex adult orthodontic cases, including the Angel Scissors-bite Turbo and Angel Enhanced Curve Turbo systems.
For pediatric and adolescent patients, the Company has developed solutions that focus on guiding growth and improving treatment efficiency during critical developmental stages. These offerings are designed to simplify treatment processes while enhancing patient comfort. In addition, Angelalign continues to support clinicians through its digital workflow platform, iOrtho, which receives biweekly updates to improve usability, treatment design capabilities, and clinical outcomes.
In lower-tier cities and regions across China, Angelalign has focused on expanding access to orthodontic care by investing in training programs, clinical support systems, and comprehensive service offerings. These efforts are aimed at helping local clinicians deliver predictable treatment outcomes, reduce treatment durations, and minimize case restarts. As a result, the Company is contributing to the overall improvement of orthodontic care standards in underserved regions.
The Company noted that some competitors have reduced their presence in lower-tier markets, which has strengthened Angelalign’s position in these regions. As awareness grows among clinicians regarding the importance of manufacturing quality, treatment planning, and clinical support, many practitioners are increasingly seeking higher-quality aligner solutions. Angelalign believes this trend is contributing to its continued growth in these markets.
In 2025, the Company’s mainland China business recorded 276,200 cases, representing a 26.3% increase year-over-year, with revenue of USD 207.3 million, up 10.1%. The Company emphasized that its efforts in lower-tier markets are not solely driven by commercial considerations, but also by a broader mission to improve access to reliable orthodontic care for both clinicians and patients.
Angelalign also highlighted that its cumulative case volume has now exceeded 2 million cases globally. The Company views this milestone as a reflection of its long-term commitment to clinical excellence and collaborative innovation. Many of these cases involve complex orthodontic treatments that require close coordination between clinicians and the Company’s support teams. This ongoing collaboration forms the foundation of Angelalign’s operating model and supports its continued growth trajectory.
Looking ahead, Angelalign plans to build on its established strengths by continuing to invest in research and development, expanding its global clinical support network, and enhancing its product portfolio. The Company believes that the clear aligner industry still has significant room for growth, driven by increasing awareness, technological advancements, and rising demand for orthodontic treatments worldwide.
By maintaining its focus on clinical quality, customer support, and innovation, Angelalign aims to sustain its momentum across both domestic and international markets. The combination of a strong organizational culture, a global operational footprint, and a commitment to continuous improvement positions the Company to further expand its leadership in the clear aligner industry in the years ahead.
About Angelalign Technology Inc.
Founded in 2003 and celebrating 2 million smiles, Angelalign Technology Inc. is a publicly listed company with a broad international shareholder base. It provides digital technology-driven clear aligner products and services in more than 60 countries.
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