
Bio-Rad Announces Financial Results for the First Quarter of 2025
Bio-Rad Laboratories, Inc. , a global leader in life science research and clinical diagnostics, released its financial results for the first quarter of 2025, reporting a modest decline in sales amid macroeconomic headwinds and industry-specific challenges. Despite a shifting economic landscape, the company demonstrated operational discipline, maintaining stable gross margins while adjusting its full-year guidance in light of increased market uncertainty.
Leadership Commentary: Navigating a Shifting Landscape
Norman Schwartz, Bio-Rad’s Chairman and Chief Executive Officer, addressed the company’s performance and outlook, noting, “We navigated a highly dynamic first quarter that became progressively more challenging, yet we delivered solid margins through focused execution and careful expense management. Given the current levels of market uncertainty, we are moderating our full-year 2025 outlook to reflect the evolving macro environment. Going forward, we remain committed to advancing our growth and margin expansion initiatives.”
The statement highlights Bio-Rad’s strategic resilience, underscoring management’s emphasis on cost discipline and long-term value creation despite near-term revenue pressures. The company remains focused on execution, particularly in balancing investments in innovation with a prudent approach to cost controls.
Financial Highlights for Q1 2025
For the first quarter ended March 31, 2025, Bio-Rad reported total net sales of $585.4 million, marking a 4.2% decrease from the $610.8 million recorded during the same quarter in 2024. When adjusted for foreign currency fluctuations, sales declined by 1.5% on a currency-neutral basis. The decline was primarily attributed to softness in the Life Science segment, with additional pressures stemming from global economic conditions and reduced reimbursements in certain markets.
Despite the dip in top-line performance, Bio-Rad maintained a gross margin of 52.3%, compared to 53.4% in the first quarter of 2024, demonstrating its ability to manage costs effectively in a revenue-constrained environment.
Segment Performance: Life Science and Clinical Diagnostics
Bio-Rad operates through two primary segments: Life Science and Clinical Diagnostics. Each exhibited distinct trends during the first quarter.
- Life Science Segment:
The Life Science division generated $228.6 million in net sales for Q1 2025, representing a 5.4% decrease compared to the same period in 2024. On a currency-neutral basis, sales were down 3.5%. The decline was primarily driven by a continued downturn in demand from academic research institutions, particularly in the Americas. Funding constraints and delays in laboratory purchasing decisions negatively impacted product demand in areas such as cell biology, protein quantitation, and gene expression analysis. The company is closely monitoring these trends while continuing to invest in technologies that address long-term growth opportunities in biopharma and translational research. - Clinical Diagnostics Segment:
The Clinical Diagnostics business generated $356.8 million in net sales during the quarter, down 3.2% year-over-year. However, on a currency-neutral basis, the segment posted a marginal decline of just 0.1%. The decrease was primarily due to reduced reimbursement rates for diabetes-related testing in China, a market that has faced recent pricing pressures from policy shifts aimed at reducing healthcare costs. This headwind was partially offset by increased global demand for Bio-Rad’s quality control products, which remain essential for clinical laboratories worldwide in maintaining assay performance and regulatory compliance.
Profitability Metrics and Earnings Highlights
Bio-Rad reported income from operations of $23.7 million for Q1 2025, down from $44.6 million in the first quarter of 2024. The decrease in operating income reflects both the decline in revenue and a slight compression in gross margins, although expense discipline mitigated some of the impact.
The company’s bottom line was significantly influenced by changes in the fair market value of its investment in Sartorius AG. This valuation adjustment contributed to a net income of $64.0 million, or $2.29 per diluted share, for the first quarter of 2025. This compares to a net income of $383.9 million, or $13.45 per diluted share, reported during the same period in 2024, when the Sartorius investment delivered exceptionally high gains due to market conditions at that time.
The effective tax rate for the first quarter stood at 23.3%, compared to 21.8% a year earlier. The increase in the tax rate was primarily driven by a shift in the geographical mix of earnings, which impacted the overall effective rate due to regional tax differences.
Non-GAAP Results Reflect Operational Strength

On a non-GAAP basis, which excludes certain items such as the impact of investment gains and other non-recurring charges, Bio-Rad posted more stable results that underscore the company’s underlying operational health:
- Non-GAAP Gross Margin: 53.8% in Q1 2025, compared to 54.2% in Q1 2024.
- Non-GAAP Income from Operations: $63.0 million for Q1 2025, an improvement over the $59.0 million reported for the same period last year.
- Non-GAAP Net Income: $71.0 million, or $2.54 per diluted share, compared to $65.3 million, or $2.30 per diluted share, in Q1 2024.
- Non-GAAP Effective Tax Rate: 20.6%, down from 22.4% in the prior-year period. The decrease in the effective tax rate was again related to geographic variations in taxable income, with more income generated in lower-tax jurisdictions during the quarter.
These figures indicate that, when normalized for non-operating factors, Bio-Rad’s core business performance remained relatively robust despite a turbulent market backdrop.
Revised 2025 Outlook Reflects Market Realities
In response to ongoing macroeconomic headwinds and segment-specific pressures, Bio-Rad revised its financial guidance for the full year 2025. The company now expects currency-neutral, non-GAAP revenue to range between a 1.0% decline and 1.5% growth. This is a downward revision from its previous guidance of 1.5% to 3.5% growth.
Additionally, Bio-Rad is adjusting its non-GAAP operating margin forecast to a range of approximately 10.0% to 12.0%, down from the prior estimate of 13.0% to 13.5%. These revisions reflect a more cautious stance in the face of continued volatility in funding cycles, geopolitical risks, and pricing dynamics in international markets.
Despite the moderated forecast, the company reaffirmed its commitment to long-term growth through continued innovation, portfolio expansion, and strategic geographic diversification. Bio-Rad continues to prioritize operational excellence and investment in key growth areas, including digital transformation of laboratory workflows, next-generation molecular diagnostics, and precision medicine tools.
Strategic Positioning for Sustainable Growth
As Bio-Rad moves through 2025, it remains focused on navigating uncertainty through a combination of disciplined cost control and strategic investments. The company’s diverse portfolio, global footprint, and strong presence in both research and clinical markets provide resilience in the face of short-term challenges.
While near-term growth may be tempered by external headwinds, Bio-Rad is well-positioned to benefit from long-term trends such as the expanding need for diagnostic infrastructure, increasing demand for personalized medicine, and growth in biotechnology research. Continued innovation, coupled with prudent financial management, will remain central to the company’s strategy as it aims to drive value for shareholders and customers alike.