- Agreement builds on Pfizer’s comprehensive strategy to work toward equitable access to COVID-19 vaccines and treatments for all people, particularly those living in the poorest parts of the world
- Agreement will enable qualified sub-licensees to supply countries comprising approximately 53% of the world’s population
- Interim data from the Phase 2/3 EPIC-HR study demonstrated an 89% reduction in risk of COVID-19-related hospitalization or death compared to placebo in non-hospitalized high-risk adults with COVID-19 within three days of symptom onset with similar results seen within five days of symptom onset
PfizerInc. and the Medicines Patent Pool (MPP), a United Nations- backed public health association working to increase access to life- saving drugs for low-and middle- income countries, moment blazoned the signing of a voluntary license agreement for Pfizer’s COVID-19 oral antiviral treatment seeker PF-07321332, which is administered in combination with low cure ritonavir (PF-07321332; ritonavir). The agreement will enable MPP to grease fresh product and distribution of the investigational antiviral, pending nonsupervisory authorization or blessing, by grantingsub-licenses to good general drug manufacturers, with the thing of easing lesser access to the global population.
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Under the terms of the head license agreement between Pfizer and MPP, good general drug manufacturers worldwide that are grantedsub-licenses will be suitable to supply PF-07321332 in combination with ritonavir to 95 countries, covering up to roughly 53 of the world’s population. This includes each low-and lower- middle- income countries and some upper-middle- income countries inSub-Saharan Africa as well as countries that have transitioned from lower- middle to upper-middle- income status in the once five times. Pfizer won’t admit royalties on deals in low- income countries and will further waive royalties on deals in all countries covered by the agreement while COVID-19 remains classified as a Public Health Emergency of International Concern by the World Health Organization.
“ Pfizer remains married to bringing forth scientific improvements to help end this epidemic for all people. We believe oral antiviral treatments can play a vital part in reducing the inflexibility of COVID-19 infections, dwindling the strain on our healthcare systems and saving lives,” said Albert Bourla, Chairman and Chief Executive Officer, Pfizer. “ We must work to insure that all people – anyhow of where they live or their circumstances – have access to these improvements, and we’re pleased to be suitable to work with MPP to further our commitment to equity.”
About PF-07321332; ritonavir
PF-07321332 is an investigational SARS-CoV-2 protease asset antiviral remedy, specifically designed to be administered orally so that it can be specified at the first sign of infection or at first mindfulness of an exposure, potentially helping cases avoid severe illness which can lead to hospitalization and death. PF-07321332 is designed to block the exertion of the SARS-CoV-2-3CL protease, an enzyme that the coronavirus needs to replicate. Co-administration with a low cure of ritonavir helps decelerate the metabolism, or breakdown, of PF-07321332 in order for it to remain active in the body for longer ages of time at advanced attention to help combat the contagion.
About Pfizer’s Commitment to Equitable Access
Pfizer is committed to working toward indifferent access of PF-07321332; ritonavir for all people, aiming to deliver safe and effective antiviral rectifiers as soon as possible and at an affordableprice.However, during the epidemic, Pfizer will offer our investigational oral antiviral remedy through a tiered pricing approach grounded on the income position of each country to promote equity of access across the globe, If authorized or approved. High and upper-middle income countries will pay further than lower income countries, which will pay a not-for- profit price.
The Medicines Patent Pool (MPP) is a United Nations- backed public health association working to increase access to, and grease the development of, life- saving drugs for low-and middle- income countries. Through its innovative business model, MPP mates with civil society, governments, transnational associations, assiduity, patient groups, and other stakeholders, to prioritize and certify demanded drugs and pool intellectual property to encourage general manufacture and the development of new phrasings. To date, MPP has inked agreements with eleven patent holders for thirteen HIV antiretrovirals, one HIV technology platform, three hepatitis C direct- acting antivirals, a tuberculosis treatment, a long- acting technology and two experimental oral antiviral treatments for COVID-19. MPP was innovated by Unitaid, which continues to be MPP’s main funder. MPP’s work on access to essential drugs is also funded by the Swiss Agency for Development and Cooperation (SDC). MPP’s conditioning in COVID-19 are accepted with the fiscal support of the Japanese Government and SDC. Further information at https//medicinespatentpool.org/ and follow us on Twitter, LinkedIn and YouTube.
About Pfizer Improvements That Change Cases’Lives
At Pfizer, we apply wisdom and our global coffers to bring curatives to people that extend and significantly ameliorate their lives. We strive to set the standard for quality, safety and value in the discovery, development and manufacture of health care products, including innovative drugs and vaccines. Every day, Pfizer associates work across developed and arising requests to advance heartiness, forestallment, treatments and cures that challenge the most stressed conditions of our time. Harmonious with our responsibility as one of the world’s premier innovative biopharmaceutical companies, we unite with health care providers, governments and original communities to support and expand access to dependable, affordable health care around the world. For further than 150 times, we’ve worked to make a difference for all who calculate on us.
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