
Scipher Medicine and Kythera Labs Join Forces to Advance Autoimmune Disease Treatment
In a groundbreaking move aimed at advancing precision medicine in the realm of autoimmune diseases, Scipher Medicine, a leading innovator in precision medicine for autoimmune conditions, has entered into a strategic partnership with Kythera Labs, a trailblazer in healthcare data and technology solutions. This collaboration promises to transform the way rheumatology treatments are discovered and developed by integrating Scipher’s pioneering real-world clinical and genomic data insights with Kythera’s state-of-the-art data technology. Together, the two companies aim to enhance precision medicine diagnostics and bring new, cutting-edge therapies to patients suffering from autoimmune diseases.
The Power of Data Integration for Precision Medicine
At the heart of this partnership lies a powerful data integration strategy that combines Scipher Medicine’s vast clinical and genomic data repository with Kythera Labs’ high-fidelity, multi-source healthcare data assets. Scipher’s rich biobank, which includes real-world data (RWD) derived from its PrismRA® platform, provides a critical foundation for the partnership. PrismRA® is a transformative precision medicine tool designed specifically for the treatment of rheumatoid arthritis (RA), one of the most common autoimmune diseases.
By integrating this wealth of real-world clinical data with Kythera’s proprietary patient mastering algorithms and advanced data technology, Scipher is poised to take precision medicine to the next level. Kythera’s technology ensures robust privacy protection while simultaneously maximizing the value of healthcare data assets. A key feature of Kythera’s platform is its ability to achieve a 98% match rate with Scipher’s data, ensuring a seamless integration between the two data systems and enabling the two companies to collaborate more effectively.
This integration of Scipher’s genomics-based, disease-specific data and Kythera’s high-quality RWD sources holds the potential to drive deeper insights into the molecular underpinnings of autoimmune diseases, specifically rheumatoid arthritis. By combining the latest advancements in data science with molecular biobank assets, the partnership will enable a more targeted approach to drug discovery, potentially leading to novel therapeutics that are more personalized and effective for patients.
Expanding the Impact of Real-World Data
The utilization of real-world data (RWD) in clinical research and drug development has been gaining momentum in recent years, and this partnership between Scipher Medicine and Kythera Labs represents a powerful step forward in leveraging this valuable data to advance rheumatology treatments. Real-world data refers to information collected from a variety of sources outside of traditional clinical trials, including electronic health records (EHRs), patient registries, insurance claims, and even mobile health data. This data provides a much more comprehensive view of patient outcomes and treatment effectiveness in real-life settings.
Kythera Labs’ cutting-edge technology enables the integration of vast and diverse real-world data sources, connecting them with the depth of Scipher’s clinico-transcriptomic biobank. Through this collaboration, the two companies are set to unlock deeper insights into how different genetic profiles respond to treatments, how disease progression occurs over time, and how environmental factors may influence disease outcomes. The goal is not only to refine and accelerate the development of new therapies but also to ensure that these therapies are personalized to meet the unique needs of individual patients.
Furthermore, the ability to integrate multi-source real-world data with genomic insights opens up new opportunities for discovering biomarkers that can be used to predict disease progression, identify patients who are most likely to benefit from specific treatments, and monitor the real-time effectiveness of therapeutic interventions. This type of data-driven approach promises to revolutionize the way rheumatology treatments are developed and prescribed, ultimately leading to better patient outcomes and more targeted interventions.
Enhancing Privacy Protection and Data Security
One of the key challenges in the use of real-world data is ensuring patient privacy and data security. Given the sensitive nature of healthcare information, it is crucial that any data integration efforts prioritize robust privacy protections to comply with regulatory requirements and build trust with patients and researchers alike. Kythera Labs addresses this concern through its innovative patient mastering algorithms, which are designed to protect patient confidentiality while enabling the effective use of healthcare data.
Kythera’s platform is engineered to deliver high-quality data insights without compromising patient privacy. By using advanced anonymization and data-matching techniques, Kythera is able to securely integrate data from a wide variety of sources, ensuring that sensitive patient information remains protected throughout the research process. This commitment to privacy protection will be crucial as Scipher Medicine and Kythera Labs expand their collaboration to include larger datasets and more diverse patient populations.
Transforming Rheumatology and Accelerating Therapy Development

The partnership between Scipher Medicine and Kythera Labs is not just about data integration—it is about transforming the future of rheumatology. By combining Scipher’s expertise in molecular diagnostics with Kythera’s data technology, the two companies are poised to accelerate the development of new, more effective therapies for patients with autoimmune diseases. Their joint efforts will allow researchers to explore new therapeutic avenues and uncover hidden patterns in disease progression that were previously difficult to detect.
Reg Seeto, CEO of Scipher Medicine, expressed his excitement about the collaboration, highlighting the potential for the partnership to drive significant advancements in personalized medicine. “This strategic partnership unites the strength of precision medicine with real-world data to accelerate the development and delivery of transformative Scipher Medicine therapies,” Seeto said. “By combining Scipher’s unique and industry-leading clinico-transcriptomic rheumatology data assets with Kythera’s data-transforming technology, we can take fuller advantage of novel data and advance personalized medicine to improve patient lives.”
The integration of Scipher’s molecular biobank with Kythera’s high-fidelity RWD platforms will also contribute to the development of new, targeted biomarkers that can guide clinical decisions and enable more Scipher Medicine precise therapeutic interventions. This will ultimately lead to better outcomes for patients and help reduce the burden of autoimmune diseases on individuals and the healthcare system as a whole.
Looking Toward the Future: Building a Bench-to-Bedside Bridge
As the partnership progresses, Scipher Medicine and Kythera Labs are focused on building a “bench-to-bedside” bridge that will facilitate the seamless translation of research discoveries into real-world clinical applications. This concept refers to the process of moving scientific discoveries from the laboratory (the “bench”) directly to patient care (the “bedside”), ensuring that new treatments reach patients faster and more efficiently.
“We are excited to partner with Scipher Medicine,” said Jeff McDonald, CEO and Co-Founder of Kythera Labs. “Our ability to integrate real-world data with high accuracy and fidelity ensures maximum data value and broad extensibility across diverse RWD use cases. By connecting the depth of Scipher’s molecular biobank data with Scipher Medicine our RWD, we can build a bench-to-bedside bridge that will assist Scipher in uncovering deeper insights and advancing the development of new therapies for patients.”
This collaborative effort represents a significant leap forward in the quest to uncover more effective and personalized treatments for autoimmune diseases. By combining Scipher’s genomic expertise with Kythera’s data technology, the two companies are laying the foundation for a new era of precision medicine that will have a lasting impact on the treatment of rheumatoid arthritis and other autoimmune conditions.
A Collaborative Future
The partnership between Scipher Medicine and Kythera Labs is a perfect example of how data-driven innovations are reshaping the healthcare landscape. By combining their strengths in precision medicine and real-world data integration, the two companies are creating new opportunities for researchers, clinicians, and patients alike. As they Scipher Medicine and Kythera Labs Join Forces to Advance Autoimmune Disease Treatment continue to collaborate, the future of rheumatology treatment discovery looks brighter than ever, with the promise of more effective, personalized therapies on the horizon.
With an eye toward improving patient outcomes, advancing scientific knowledge, and accelerating the development of new treatments, Scipher and Kythera are not only transforming the field of rheumatology but also setting the stage for a future where precision medicine becomes the standard of care for autoimmune diseases. This partnership is a clear indication that the integration of real-world data and cutting-edge technology will be essential in shaping the next generation of medical breakthroughs.