Results of nationally representative survey come as the ACIP evaluates data to provide guidance for flu vaccines in this vulnerable population
A majority (66%) of surveyed healthcare providers (HCPs) in the U.S. said that if they could recommend to the CDC one influenza vaccine for adults 65 years and older (65+), they would choose a vaccine with the clinical profile of Fluzone High-Dose Quadrivalent (Influenza Vaccine), according to a survey of 700 U.S. HCPs conducted by Ipsos, the world’s third-largest insights and analytical company and sponsored by Sanofi.1
Two-thirds (66%) of the HCPs said that if they were voting members of the CDC’s Advisory Committee on Immunization Practices (ACIP), they would recommend the use of a vaccine like Fluzone High-Dose Quadrivalent for adults 65+.1 HCP responses to the blinded survey cited reasons for preference, including the vaccine’s superior efficacy compared to a standard-dose influenza vaccine and total years evaluated in real-world studies. The survey results underscore the importance of an ACIP preferential recommendation and come as the ACIP evaluates data to provide guidance for flu vaccines in this vulnerable population.
The 65+ Flu Vaccines HCP Preference Survey was designed to evaluate HCP influenza vaccine brand preference for three different influenza vaccines. When presented with blinded clinical profiles of the three vaccines, nearly 74% of HCPs said they would recommend a vaccine with the clinical profile of Fluzone® High-Dose Quadrivalent for patients 65+ over another flu vaccine designed for this population, or over a standard-dose influenza vaccine.1
Other key takeaways from the survey included:
76% of HCPs would recommend a vaccine with the clinical profile of Fluzone High-Dose Quadrivalent for their family and friends, if over 65+.1
72% of HCPs would prefer a vaccine with the clinical profile of Fluzone High-Dose Quadrivalent for themselves, if over 65+.1
96% of HCPs are very or somewhat likely to follow ACIP guidance when vaccinating adults 65+ for seasonal flu.1
Michael Greenberg, MD
North America Medical Head of Vaccines at Sanofi
“Given the importance of protecting this vulnerable population from the flu, this new survey underscores the need for clear and specific guidance, ideally with a recommendation for Fluzone High-Dose Quadrivalent, based on demonstrated clinical results and real-world evidence. In fact, most healthcare professionals surveyed said they would prefer a vaccine with the clinical profile of Fluzone High-Dose Quadrivalent for themselves, their family and friends.1 This guidance could help to improve patient and provider confidence, patient outcomes, and access for patients to the recommended vaccine.
With protection against four flu strains, Fluzone High-Dose is the only influenza vaccine licensed for use in adults 65 years of age and older to have demonstrated superior efficacy in a randomized controlled trial versus a standard dose influenza vaccine for the prevention of laboratory-confirmed influenza illness and the only influenza vaccine with 10 years of data demonstrating protection from flu and its related complications.5,6 a,b In a meta-analysis of 15 published reports, including approximately 34 million people, those who received Fluzone High-Dose experienced approximately an 18% reduction in cardiorespiratory hospitalizations and over a 27% decrease in pneumonia hospitalizations, both of which are reductions above what the standard dose vaccines provided.6
a Proven superiority in a clinical trial between Fluzone High-Dose (Influenza Vaccine) (trivalent formulation) and a standard-dose influenza vaccine5
b Includes 10 years of evidence (2009-2019) with Fluzone High-Dose (trivalent formulation)6
About the 65+ Flu Vaccines Healthcare Professional Preference Survey
The 65+ Flu Vaccines HCP Preference Survey was conducted online among 700 licensed primary care physicians, pharmacists, cardiologists and pulmonologists within the United States by Ipsos, the world’s third-largest insights and analytics company, on behalf of Sanofi from March 9 to 23, 2022. The survey was designed to evaluate HCP influenza vaccine preference between three different influenza vaccine options in a blinded format (Fluzone High-Dose Quadrivalent , Fluzone Quadrivalent (Influenza Vaccine) and Fluad Quadrivalent (Influenza Vaccine, Adjuvanted)). The sample size, the range of demographics, and practice type suggest that the results are relevant of the flu administering population. The 65+ HCP Preference Survey was reviewed and approved by independent review board (IRB) Salus, an AAHRP-accredited IRB. This survey was not designed to compare the efficacy and safety of the three vaccines used in this survey.
About Fluzone High-Dose Quadrivalent
Fluzone High-Dose Quadrivalent is a vaccine indicated for prevention of influenza disease caused by influenza A and B strains contained in the vaccine. Fluzone High-Dose Quadrivalent is given to people 65 years of age and older.5
Fluzone High-Dose is the only vaccine approved by the U.S. FDA for superior flu protection in adults 65 years of age and older, compared to a standard-dose flu vaccine.5 With 4-strain protection, Fluzone High-Dose Quadrivalent builds on the legacy of the trivalent formulation, which was clinically proven to be 24.2% more effective at preventing flu than standard-dose Fluzone (Influenza Vaccine) in adults 65+.7 Based on data from Fluzone High-Dose (Influenza Vaccine), side effects were slightly more frequent after vaccination with Fluzone High-Dose compared to a standard-dose vaccine.8
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