Learning how to control HIV from African genomes Despite significant advances in treatment and access to therapy, the human immunodeficiency virus remains a global health challenge with almost 40 million affected individuals, no vaccine and no cure. The virus attacks…
New RNA-based therapy combats melanoma in mouse models Investigators at the Icahn School of Medicine at Mount Sinai have designed an innovative RNA-based strategy to activate dendritic cells – which play a key role in immune response – that eradicated…
Unlocking the mystery of long-lasting cancer treatmentUnlocking the mystery of long-lasting cancer treatment New insights explaining why some children have a longer remission than others after having cutting-edge CAR T-cell therapy for leukaemia have been revealed by researchers at UCL,…
Artificial cells demonstrate that “life finds a way” Listen, if there’s one thing the history of evolution has taught us is that life will not be contained. Life breaks free. It expands to new territories, and it crashes through barriers…
The new approach in cancer therapy with innovative mechanism-of-action for ferroptosis induction A team of researchers led by Dr. Marcus Conrad from Helmholtz Munich discovered a novel anti-cancer drug, called icFSP1, which sensitizes cancer cells to ferroptosis. Ferroptosis is characterized…
Magdeburg researchers discover a new mechanism of cancer immune defense Modern immunotherapies boost the body’s own defenses against cancer. They activate killer T cells of the immune system that can specifically recognize and destroy cancer cells. In many patients, however,…
New anti-coagulants may help treat sepsis and COVID-19 Scientists from Trinity College Dublin have just discovered that the drug dimethylfumarate can block blood clotting during infection, offering hope that it could be used to treat a number of conditions, such…
For resistant breast cancers, two drugs may be better than one Cancer cells are even smarter than scientists previously believed, according to new CU Boulder research. When these cells are confronted with potent new drugs called CDK2 inhibitors, which are…
First-Of-Its-Kind Head-to-Head Clinical Trial Reaffirms the Efficacy of Emgality in Episodic Migraine Prevention Eli Lilly and Company (NYSE: LLY) announced results of the CHALLENGE-MIG clinical trial of Emgality® (galcanezumab-gnlm) and Nurtec® ODT (rimegepant orally disintegrating tablet), the first and only trial of its…
Scientists discover small RNA that regulates bacterial infection People with weakened immune systems are at constant risk of infection. Pseudomonas aeruginosa, a common environmental bacterium, can colonize different body parts, such as the lungs, leading to persistent, chronic infections that…
Taurine may be a key to longer and healthier life A deficiency of taurine – a nutrient produced in the body and found in many foods – is a driver of aging in animals, according to a new study led…
WHO launches a single-source repository on drug dependence information The repository, from WHO’s Expert Committee on Drug Dependence (ECDD), is an important resource for health professionals, drug policy experts and policy-makers, as many of the substances reviewed by ECDD have otherwise…