Pfizer and Alliance Foundation Trials, LLC (AFT) recently unveiled findings from the Phase 3 PATINA trial, highlighting the potential of IBRANCE (palbociclib) in improving outcomes for patients with hormone receptor-positive (HR+), human epidermal growth factor receptor 2-positive (HER2+) metastatic breast…
Cyrus Biotechnology, Inc. has announced new data demonstrating the potent activity of its engineered IgG-degrading enzyme, CYR241, in a rabbit redosing model. Importantly, the study revealed that CYR241 does not induce anti-drug antibodies (ADAs) after repeat administrations at therapeutic doses,…
Menarini Group, Stemline Therapeutics, and MEDSIR have presented groundbreaking research on the ADELA clinical trial, which targets therapeutic resistance in advanced ER+/HER2- breast cancer. This research was shared at the San Antonio Breast Cancer Symposium 2024 (SABCS). ADELA is a…
Sirius Therapeutics has announced promising preliminary results from its Phase 1 first-in-human clinical trial of SRSD107, a next-generation siRNA therapeutic under development for the prevention and treatment of thromboembolic disorders. These include conditions such as myocardial infarction, ischemic stroke, and…
SK pharmteco, a global leader in contract development, manufacturing, and analytical testing services for the pharmaceutical and cell & gene therapy industries, has announced a groundbreaking brand unification initiative. This strategic effort consolidates the expertise and capabilities of several renowned…
Agilent Technologies today announced the issuance of a Class C Companion Diagnostic (CDx) In Vitro Diagnostic Regulation (IVDR) certification for its PD-L1 IHC 28-8 pharmDx (Code SK005) assay. This diagnostic tool, which had previously received CE-IVD marking for sales within…
At the 66th Annual Meeting of the American Society of Hematology (ASH), AbbVie shared new data from two ongoing clinical trials evaluating epcoritamab, a CD3xCD20 bispecific T-cell-engaging antibody. Administered subcutaneously, epcoritamab demonstrated encouraging outcomes in adult patients with diffuse large…
Regeneron Pharmaceuticals, Inc. (NASDAQ: REGN) announced updated Phase 3 data from the ACCESS-1 trial, showing that its investigational combination of pozelimab and cemdisiran (poze-cemdi) outperforms the standard-of-care C5 inhibitor, ravulizumab, in patients with paroxysmal nocturnal hemoglobinuria (PNH). The results, presented…
Genmab has announced promising results from the Phase 1b/2 EPCORE® NHL-2 trial, which evaluated a fixed-duration regimen of epcoritamab, a T-cell engaging bispecific antibody, in combination with lenalidomide and rituximab (R2) in adult patients with relapsed or refractory (R/R) follicular…
Genmab has announced promising results from the Phase 1b/2 EPCORE® CLL-1 clinical trial evaluating epcoritamab, a T-cell engaging bispecific antibody, in patients with relapsed or refractory chronic lymphocytic leukemia (R/R CLL). Epcoritamab, administered subcutaneously as monotherapy, demonstrated an overall response…
Stoke Therapeutics has announced new data from its Phase 1/2a and open-label extension (OLE) studies on zorevunersen, a potential disease-modifying treatment for Dravet syndrome. The data revealed significant and lasting reductions in convulsive seizure frequency in patients who received zorevunersen…
Alithea Genomics, a leading innovator in large-scale RNA sequencing and transcriptomics, has unveiled its latest technological advancement: the MERCURIUS™ Full-Length DRUG-seq library preparation platform. This new solution represents a groundbreaking approach in RNA sequencing, combining massive sample multiplexing, an extraction-free…